Basic Information
ID: ALA4376380
Type: Binding
Description: Transactivation of Gal4-fused human PPARgamma transfected in COS7 cells co-transfected with pGAL5-TK-pGL3 and pRennilla-CMV assessed as maximum intrinsic activation at 10 uM incubated for 39 hrs by dual luciferase reporter assay relative to pioglitazone
Format: BAO_0000219
Organism: Homo sapiens
Target: Peroxisome proliferator-activated receptor gamma(ALA235)
Document: ALA4373734
Transactivation of Gal4-fused human PPARgamma transfected in COS7 cells co-transfected with pGAL5-TK-pGL3 and pRennilla-CMV assessed as maximum intrinsic activation at 10 uM incubated for 39 hrs by dual luciferase reporter assay relative to pioglitazone: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4376380
Intrinsic activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 514.63 | 7.26 | 7.26 |
| 415.45 | 5.31 | 5.31 |
| 370.45 | 5.40 | 5.40 |
| 369.47 | 4.80 | 4.80 |
| 388.44 | 5.54 | 5.54 |
| 400.48 | 5.41 | 5.41 |
| 414.47 | 4.71 | 4.71 |
| 387.46 | 4.94 | 4.94 |
| 384.48 | 5.71 | 5.71 |
| 437.47 | 5.82 | 5.82 |
| 384.48 | 4.39 | 4.39 |
| 403.91 | 5.46 | 5.46 |
| 438.45 | 6.42 | 6.42 |
| 448.36 | 5.57 | 5.57 |
| 404.90 | 6.06 | 6.06 |
| 399.49 | 4.81 | 4.81 |
| 383.50 | 5.11 | 5.11 |
| 385.47 | 4.98 | 4.98 |
| 449.35 | 6.16 | 6.16 |
| 386.45 | 5.11 | 5.11 |
| 385.47 | 4.51 | 4.51 |