Basic Information
ID: ALA4376383
Type: Functional
Description: Induction of sensitization to imatinib-induced cytotoxicity in imatinib-resistant human K562-IMA[r] cells assessed as induction of cell death at 10 uM after 72 hrs in presence of 1 uM imatinib by propidium iodide/Triton-X100 dye based FACS analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: K562-IMA[r]
Target: K562-IMA[r](ALA4483249)
Document: ALA4373734
Induction of sensitization to imatinib-induced cytotoxicity in imatinib-resistant human K562-IMA[r] cells assessed as induction of cell death at 10 uM after 72 hrs in presence of 1 uM imatinib by propidium iodide/Triton-X100 dye based FACS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4376383
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 356.45 | 3.16 | 3.16 |
| 514.63 | 7.26 | 7.26 |
| 415.45 | 5.31 | 5.31 |
| 370.45 | 5.40 | 5.40 |
| 388.44 | 5.54 | 5.54 |
| 400.48 | 5.41 | 5.41 |
| 414.47 | 4.71 | 4.71 |
| 384.48 | 5.71 | 5.71 |
| 384.48 | 4.39 | 4.39 |
| 438.45 | 6.42 | 6.42 |
| 404.90 | 6.06 | 6.06 |
| 399.49 | 4.81 | 4.81 |
| 385.47 | 4.98 | 4.98 |
| 449.35 | 6.16 | 6.16 |
| 386.45 | 5.11 | 5.11 |
| 385.47 | 4.51 | 4.51 |