Basic Information
ID: ALA4376394
Type: Functional
Description: Induction of sensitization to imatinib-induced cytotoxicity in imatinib-resistant human K562-IMA[r] cells assessed as induction of cell death at 10 uM after 72 hrs in presence of 1 uM imatinib by propidium iodide/Triton-X100 dye based FACS analysis (Rvb = 15%)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: K562-IMA[r]
Target: K562-IMA[r](ALA4483249)
Document: ALA4373734
Induction of sensitization to imatinib-induced cytotoxicity in imatinib-resistant human K562-IMA[r] cells assessed as induction of cell death at 10 uM after 72 hrs in presence of 1 uM imatinib by propidium iodide/Triton-X100 dye based FACS analysis (Rvb = 15%): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4376394
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.47 | 4.80 | 4.80 |
| 387.46 | 4.94 | 4.94 |
| 437.47 | 5.82 | 5.82 |
| 403.91 | 5.46 | 5.46 |
| 448.36 | 5.57 | 5.57 |
| 383.50 | 5.11 | 5.11 |