Basic Information
ID: ALA4376421
Type: Binding
Description: Inhibition of human recombinant N-terminal His-tagged SIRT1 (1 to 747 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate after 30 mins in presence of NAD+ by fluorimetry analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: NAD-dependent deacetylase sirtuin 1(ALA4506)
Document: ALA4373735
Inhibition of human recombinant N-terminal His-tagged SIRT1 (1 to 747 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate after 30 mins in presence of NAD+ by fluorimetry analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4376421
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 485.58 | 4.67 | 4.67 |
| 471.55 | 4.28 | 4.28 |