Basic Information
ID: ALA4376440
Type: Functional
Description: Cytoprotective activity against OGD/reperfusion induced injury in Sprague-Dawley rat cardiomyocytes assessed as effect on cell viability at 10 uM pretreated for 24 hrs followed by OGD for 2 hrs and subsequent reperfusion for 24 hrs (Rvb = 43.9 to 45.4 +/- 1.1 %)
Format: BAO_0000219
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Cell type: Cardiac muscle cell
Target: Cardiac muscle cell(ALA4296517)
Document: ALA4373736
Cytoprotective activity against OGD/reperfusion induced injury in Sprague-Dawley rat cardiomyocytes assessed as effect on cell viability at 10 uM pretreated for 24 hrs followed by OGD for 2 hrs and subsequent reperfusion for 24 hrs (Rvb = 43.9 to 45.4 +/- 1.1 %): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4376440
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 476.74 | 5.71 | 5.71 |
| 545.81 | 7.75 | 7.75 |
| 563.80 | 7.89 | 7.89 |
| 629.80 | 8.65 | 8.65 |
| 570.84 | 6.69 | 6.69 |
| 592.84 | 7.39 | 7.39 |
| 543.75 | 5.75 | 5.75 |
| 570.84 | 6.03 | 6.03 |
| 527.82 | 7.04 | 7.04 |
| 618.86 | 6.95 | 6.95 |
| 508.75 | 6.06 | 6.06 |
| 559.84 | 8.06 | 8.06 |
| 624.33 | 9.05 | 9.05 |
| 590.87 | 7.79 | 7.79 |
| 657.88 | 9.42 | 9.42 |
| 530.82 | 6.10 | 6.10 |
| 552.83 | 6.80 | 6.80 |
| 568.87 | 7.33 | 7.33 |
| 571.80 | 6.23 | 6.23 |
| 574.85 | 7.25 | 7.25 |
| 563.80 | 7.89 | 7.89 |
| 624.89 | 6.40 | 6.40 |
| 499.74 | 6.05 | 6.05 |
| 575.83 | 7.76 | 7.76 |
| 555.87 | 7.85 | 7.85 |
| 592.68 | 7.49 | 7.49 |
| 529.76 | 5.55 | 5.55 |
| 510.76 | 5.85 | 5.85 |
| 528.80 | 6.31 | 6.31 |
| 542.83 | 6.77 | 6.77 |
| 646.91 | 7.43 | 7.43 |
| 570.82 | 5.96 | 5.96 |
| 585.85 | 6.91 | 6.91 |
| 566.75 | 6.81 | 6.81 |
| 498.75 | 5.79 | 5.79 |
| 604.88 | 6.74 | 6.74 |
| 580.25 | 8.41 | 8.41 |
| 604.90 | 8.47 | 8.47 |
| 619.91 | 8.41 | 8.41 |
| 598.24 | 8.55 | 8.55 |
| 589.89 | 8.40 | 8.40 |
| 528.78 | 5.28 | 5.28 |