Basic Information
ID: ALA4376600
Type: Binding
Description: Inhibition of recombinant human GST-tagged ROS1 catalytic domain (1883 to 2347 residues) expressed in baculovirus expression system at 1 uM using biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 to 60 mins in presence of ATP by HTRF assay relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: Proto-oncogene tyrosine-protein kinase ROS(ALA5568)
Document: ALA4373740
Inhibition of recombinant human GST-tagged ROS1 catalytic domain (1883 to 2347 residues) expressed in baculovirus expression system at 1 uM using biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 to 60 mins in presence of ATP by HTRF assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4376600
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.54 | 6.16 | 6.16 |