ID: ALA4376722
Type: ADME
Description: Unbound tissue partition coefficient, ratio of drug level in adipose to plasma in Wistar Han rat at 1 to 2 mg/kg, iv infused for 10 to 20 hrs by LC-MS/MS analysis
Organism: Rattus norvegicus
Strain: Wistar Han
Tissue: Adipose tissue/Plasma
Bioactivity
Activity Types for Assay ALA4376722
Ratio
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
383.41 | 1.78 | 1.78 |
531.44 | 4.21 | 4.21 |
401.85 | 3.30 | 3.30 |
477.05 | 5.09 | 5.09 |
720.96 | 5.91 | 5.91 |
200.22 | 0.79 | 0.79 |
259.05 | 2.34 | 2.34 |
239.32 | 1.28 | 1.28 |
386.44 | 1.52 | 1.52 |
419.50 | 5.10 | 5.10 |
514.67 | 4.54 | 4.54 |
351.33 | 3.11 | 3.11 |
479.50 | 4.18 | 4.18 |
504.65 | 5.07 | 5.07 |
439.39 | 3.08 | 3.08 |
347.85 | 3.76 | 3.76 |
204.01 | 2.84 | 2.84 |
457.53 | 5.15 | 5.15 |
503.52 | 5.63 | 5.63 |
450.41 | 4.75 | 4.75 |
452.51 | 1.33 | 1.33 |
379.47 | 2.11 | 2.11 |
534.95 | 6.06 | 6.06 |
302.72 | 3.59 | 3.59 |
481.61 | 0.83 | 0.83 |
337.78 | 3.74 | 3.74 |
398.85 | 3.59 | 3.59 |
527.60 | 4.46 | 4.46 |
353.33 | 4.02 | 4.02 |
428.93 | 2.65 | 2.65 |
439.90 | 3.23 | 3.23 |
495.97 | 3.39 | 3.39 |
368.46 | 2.65 | 2.65 |
305.38 | 2.38 | 2.38 |
319.33 | 1.33 | 1.33 |
441.46 | 2.90 | 2.90 |
341.37 | 1.25 | 1.25 |
484.04 | 3.99 | 3.99 |
434.50 | 2.49 | 2.49 |
539.60 | 3.74 | 3.74 |
353.43 | 1.63 | 1.63 |
408.56 | 3.31 | 3.31 |
500.52 | 5.57 | 5.57 |
211.25 | 0.38 | 0.38 |
251.33 | 3.30 | 3.30 |
452.53 | 4.55 | 4.55 |
520.48 | 3.65 | 3.65 |
539.60 | 3.74 | 3.74 |
519.36 | 4.54 | 4.54 |
411.76 | 4.12 | 4.12 |
493.62 | 5.86 | 5.86 |
469.59 | 2.66 | 2.66 |
268.32 | 4.28 | 4.28 |
380.52 | 4.26 | 4.26 |
470.45 | 4.95 | 4.95 |
369.42 | 2.12 | 2.12 |