Basic Information
ID: ALA4376724
Type: ADME
Description: Unbound tissue partition coefficient, ratio of drug level in skeletal muscle to plasma in Wistar Han rat at 1 to 2 mg/kg, iv infused for 10 to 20 hrs by LC-MS/MS analysis
Organism: Rattus norvegicus
Strain: Wistar Han
Tissue: Muscle tissue/plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4376724
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 1.78 | 1.78 |
| 531.44 | 4.21 | 4.21 |
| 401.85 | 3.30 | 3.30 |
| 477.05 | 5.09 | 5.09 |
| 720.96 | 5.91 | 5.91 |
| 200.22 | 0.79 | 0.79 |
| 259.05 | 2.34 | 2.34 |
| 239.32 | 1.28 | 1.28 |
| 386.44 | 1.52 | 1.52 |
| 419.50 | 5.10 | 5.10 |
| 514.67 | 4.54 | 4.54 |
| 351.33 | 3.11 | 3.11 |
| 479.50 | 4.18 | 4.18 |
| 504.65 | 5.07 | 5.07 |
| 439.39 | 3.08 | 3.08 |
| 347.85 | 3.76 | 3.76 |
| 204.01 | 2.84 | 2.84 |
| 457.53 | 5.15 | 5.15 |
| 503.52 | 5.63 | 5.63 |
| 450.41 | 4.75 | 4.75 |
| 452.51 | 1.33 | 1.33 |
| 379.47 | 2.11 | 2.11 |
| 534.95 | 6.06 | 6.06 |
| 302.72 | 3.59 | 3.59 |
| 481.61 | 0.83 | 0.83 |
| 337.78 | 3.74 | 3.74 |
| 398.85 | 3.59 | 3.59 |
| 527.60 | 4.46 | 4.46 |
| 353.33 | 4.02 | 4.02 |
| 428.93 | 2.65 | 2.65 |
| 439.90 | 3.23 | 3.23 |
| 495.97 | 3.39 | 3.39 |
| 368.46 | 2.65 | 2.65 |
| 305.38 | 2.38 | 2.38 |
| 319.33 | 1.33 | 1.33 |
| 441.46 | 2.90 | 2.90 |
| 341.37 | 1.25 | 1.25 |
| 484.04 | 3.99 | 3.99 |
| 434.50 | 2.49 | 2.49 |
| 539.60 | 3.74 | 3.74 |
| 353.43 | 1.63 | 1.63 |
| 408.56 | 3.31 | 3.31 |
| 500.52 | 5.57 | 5.57 |
| 211.25 | 0.38 | 0.38 |
| 251.33 | 3.30 | 3.30 |
| 452.53 | 4.55 | 4.55 |
| 520.48 | 3.65 | 3.65 |
| 539.60 | 3.74 | 3.74 |
| 519.36 | 4.54 | 4.54 |
| 411.76 | 4.12 | 4.12 |
| 493.62 | 5.86 | 5.86 |
| 469.59 | 2.66 | 2.66 |
| 268.32 | 4.28 | 4.28 |
| 380.52 | 4.26 | 4.26 |
| 470.45 | 4.95 | 4.95 |
| 369.42 | 2.12 | 2.12 |