Basic Information
ID: ALA4376799
Type: ADME
Description: Prodrug conversion in PBS containing 5% DMSO assessed as Escherichia coli nitroreductase-mediated activation by measuring release of ethyl (6R)-6-[(2-chloro-4-fluorophenyl)sulfamoyl]cyclohexene-1-carboxylate parent drug at 0.01 mg/ml at pH 7.4 in presence of NADH by HPLC analysis
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4376799
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 496.94 | 4.77 | 4.77 |
| 540.95 | 4.90 | 4.90 |