Assay Report Card

Basic Information

ID: ALA4376800

Type: ADME

Description: Prodrug conversion in PBS containing 5% DMSO assessed as Escherichia coli nitroreductase-mediated activation by measuring reduced amine intermediate metabolite formation at 0.01 mg/ml at pH 7.4 in presence of NADH by HPLC analysis

Organism: Escherichia coli

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
496.944.774.77
540.954.904.90