ID: ALA4376800
Type: ADME
Description: Prodrug conversion in PBS containing 5% DMSO assessed as Escherichia coli nitroreductase-mediated activation by measuring reduced amine intermediate metabolite formation at 0.01 mg/ml at pH 7.4 in presence of NADH by HPLC analysis
Organism: Escherichia coli
Bioactivity
Activity Types for Assay ALA4376800
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
496.94 | 4.77 | 4.77 |
540.95 | 4.90 | 4.90 |