Basic Information
ID: ALA4377078
Type: Binding
Description: Inhibition of TRPC5 (unknown origin) expressed in HEK293/TREx cells assessed as reduction in intracellular calcium level measured for 3 mins by fluo4 dye-based fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Short transient receptor potential channel 5(ALA1250411)
Document: ALA4376804
Inhibition of TRPC5 (unknown origin) expressed in HEK293/TREx cells assessed as reduction in intracellular calcium level measured for 3 mins by fluo4 dye-based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4377078
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.85 | 2.77 | 2.77 |
| 459.33 | 4.24 | 4.24 |
| 486.51 | 3.79 | 3.79 |
| 524.95 | 4.95 | 4.95 |
| 399.30 | 3.43 | 3.43 |
| 364.85 | 2.77 | 2.77 |
| 503.38 | 4.09 | 4.09 |
| 556.95 | 4.57 | 4.57 |
| 399.30 | 3.43 | 3.43 |
| 416.40 | 3.28 | 3.28 |
| 348.40 | 2.26 | 2.26 |
| 475.40 | 4.71 | 4.71 |
| 475.40 | 4.71 | 4.71 |
| 491.40 | 4.83 | 4.83 |
| 364.85 | 2.77 | 2.77 |
| 365.84 | 2.17 | 2.17 |
| 470.51 | 4.30 | 4.30 |
| 366.39 | 2.40 | 2.40 |
| 380.47 | 3.27 | 3.27 |
| 540.95 | 5.08 | 5.08 |
| 491.40 | 4.20 | 4.20 |
| 414.41 | 3.02 | 3.02 |
| 414.41 | 3.02 | 3.02 |
| 397.35 | 2.28 | 2.28 |
| 452.90 | 2.91 | 2.91 |
| 553.46 | 4.90 | 4.90 |
| 477.99 | 4.51 | 4.51 |
| 363.46 | 1.85 | 1.85 |
| 383.45 | 1.86 | 1.86 |
| 458.35 | 3.91 | 3.91 |
| 470.89 | 3.05 | 3.05 |
| 535.91 | 4.41 | 4.41 |
| 415.92 | 3.39 | 3.39 |
| 484.47 | 4.24 | 4.24 |
| 570.45 | 4.17 | 4.17 |
| 459.55 | 3.98 | 3.98 |
| 554.45 | 4.29 | 4.29 |
| 414.48 | 2.99 | 2.99 |
| 450.92 | 4.12 | 4.12 |
| 493.99 | 4.00 | 4.00 |
| 453.90 | 3.53 | 3.53 |
| 465.47 | 3.88 | 3.88 |
| 400.45 | 2.60 | 2.60 |
| 423.56 | 3.86 | 3.86 |
| 469.90 | 3.65 | 3.65 |
| 353.42 | 2.27 | 2.27 |
| 485.46 | 3.63 | 3.63 |
| 412.49 | 2.56 | 2.56 |
| 507.90 | 4.15 | 4.15 |
| 423.56 | 3.86 | 3.86 |
| 514.50 | 4.75 | 4.75 |
| 477.54 | 4.12 | 4.12 |
| 520.90 | 3.93 | 3.93 |
| 419.46 | 2.87 | 2.87 |
| 501.47 | 2.98 | 2.98 |
| 500.47 | 4.36 | 4.36 |
| 481.47 | 3.76 | 3.76 |
| 533.93 | 4.21 | 4.21 |
| 487.34 | 3.56 | 3.56 |
| 361.83 | 1.89 | 1.89 |
| 401.44 | 1.99 | 1.99 |
| 486.36 | 4.17 | 4.17 |
| 486.36 | 4.17 | 4.17 |
| 520.90 | 3.68 | 3.68 |
| 458.35 | 3.91 | 3.91 |
| 411.38 | 2.30 | 2.30 |
| 431.92 | 3.51 | 3.51 |
| 518.46 | 4.50 | 4.50 |
| 497.47 | 3.25 | 3.25 |
| 372.40 | 1.82 | 1.82 |
| 479.50 | 3.56 | 3.56 |
| 477.99 | 4.51 | 4.51 |
| 415.92 | 3.39 | 3.39 |
| 521.92 | 4.46 | 4.46 |
| 514.37 | 4.74 | 4.74 |
| 417.89 | 2.51 | 2.51 |
| 397.35 | 1.99 | 1.99 |
| 400.45 | 2.60 | 2.60 |
| 466.93 | 3.22 | 3.22 |