Basic Information
ID: ALA4377382
Type: Binding
Description: Inhibition of TYK2 in mouse whole blood assessed as decrease in IFNalpha-induced STAT1 phosphorylation preincubated for 1 hr followed by stimulation with IFN-alpha for 15 mins by fluorescence analysis
Organism: Mus musculus
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4377382
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.49 | 3.58 | 3.58 |
| 425.47 | 1.73 | 1.73 |
| 463.47 | 4.14 | 4.14 |
| 462.49 | 3.87 | 3.87 |
| 455.48 | 3.00 | 3.00 |
| 421.46 | 2.34 | 2.34 |
| 449.45 | 3.83 | 3.83 |
| 462.49 | 3.58 | 3.58 |
| 498.47 | 4.15 | 4.15 |
| 462.49 | 3.58 | 3.58 |
| 461.50 | 4.18 | 4.18 |
| 424.48 | 2.34 | 2.34 |
| 461.50 | 4.18 | 4.18 |
| 448.46 | 3.56 | 3.56 |
| 459.51 | 3.14 | 3.14 |