Basic Information
ID: ALA4377390
Type: ADME
Description: Inhibition of JAK1/JAK3 in human PBMC assessed as decrease in IL2-induced STAT5 phosphorylation in CD3+ T cells preincubated for 1 hr followed by stimulation with IL2 for 15 mins by flow cytometry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4377390
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.47 | 1.73 | 1.73 |
| 401.47 | 2.12 | 2.12 |