Basic Information
ID: ALA4378184
Type: Binding
Description: Inhibition of LTC4S in zymosan-stimulated human PBMC assessed as inhibition of LTC4 production preincubated for 45 mins followed by zymosan stimulation and measured after 20 mins by LC-MS/MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4378184
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 473.40 | 4.43 | 4.43 |
| 457.84 | 4.21 | 4.21 |
| 454.42 | 4.95 | 4.95 |
| 454.42 | 4.90 | 4.90 |
| 422.40 | 4.56 | 4.56 |
| 366.42 | 3.54 | 3.54 |
| 436.90 | 5.22 | 5.22 |
| 434.47 | 4.83 | 4.83 |
| 435.31 | 4.85 | 4.85 |
| 462.35 | 4.71 | 4.71 |
| 450.92 | 5.35 | 5.35 |
| 451.91 | 4.74 | 4.74 |
| 494.50 | 5.18 | 5.18 |
| 436.48 | 5.08 | 5.08 |
| 400.86 | 4.20 | 4.20 |
| 452.43 | 3.92 | 3.92 |
| 418.85 | 4.33 | 4.33 |
| 408.43 | 4.44 | 4.44 |
| 408.38 | 4.17 | 4.17 |
| 436.84 | 4.47 | 4.47 |
| 452.40 | 4.70 | 4.70 |
| 439.85 | 4.11 | 4.11 |
| 456.85 | 4.81 | 4.81 |
| 422.46 | 4.83 | 4.83 |
| 488.44 | 5.49 | 5.49 |
| 452.94 | 5.88 | 5.88 |
| 455.41 | 4.34 | 4.34 |
| 434.41 | 4.56 | 4.56 |
| 436.43 | 4.81 | 4.81 |
| 438.86 | 4.72 | 4.72 |
| 418.85 | 4.33 | 4.33 |
| 472.41 | 5.04 | 5.04 |