Basic Information
ID: ALA4378770
Type: Binding
Description: Inhibition of N-terminal His6 tagged human TEAD4-YBD (217 to 434 residues) expressed in Escherichia coli C43 (DE3) cells assessed as reduction in autopalmitoylation at 800 nM preincubated for 2 hrs followed by palmitoyl alkyne-coenzyme A addition and measured after 30 mins by immunoblot analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4378770
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 233.29 | 2.73 | 2.73 |
| 339.42 | 4.02 | 4.02 |
| 323.42 | 4.32 | 4.32 |
| 342.42 | 2.77 | 2.77 |
| 273.36 | 3.16 | 3.16 |
| 357.44 | 2.47 | 2.47 |
| 289.36 | 3.15 | 3.15 |
| 422.55 | 4.45 | 4.45 |
| 276.31 | 3.33 | 3.33 |
| 275.33 | 3.36 | 3.36 |
| 339.42 | 4.02 | 4.02 |
| 352.42 | 3.98 | 3.98 |