Basic Information
ID: ALA4379013
Type: Binding
Description: Displacement of TMR-labelled PDI from human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells preincuabted for 1 hr with TMR-labelled PDI followed by compound addition and measured after 1 hr by fluorescence polarization assay
Format: BAO_0000219
Organism: Homo sapiens
Target: p53-binding protein Mdm-2(ALA5023)
Document: ALA4376831
Displacement of TMR-labelled PDI from human GST tagged MDM2 (1 to 139 residues) expressed in Escherichia coli BL21 (DE3) cells preincuabted for 1 hr with TMR-labelled PDI followed by compound addition and measured after 1 hr by fluorescence polarization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4379013
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 3418.98 | ||
| 1835.10 | ||
| 2915.37 | ||
| 2839.27 | ||
| 3282.83 | ||
| 2745.15 |