Basic Information
ID: ALA4379075
Type: Binding
Description: Inhibition of recombinant human ROCK1 (17 to 535 residues) using KEAKEKRQEQIAKR as substrate incubated for 40 mins in presence of [gamma-33P]ATP and 10 uM ATP by radiometric scintillation counting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4379075
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.41 | 3.97 | 3.97 |
| 457.49 | 4.13 | 4.13 |
| 429.43 | 3.65 | 3.65 |
| 471.51 | 3.81 | 3.81 |
| 518.47 | 4.63 | 4.63 |
| 489.43 | 4.54 | 4.54 |
| 444.44 | 4.07 | 4.07 |
| 449.48 | 4.36 | 4.36 |
| 461.47 | 4.35 | 4.35 |
| 493.31 | 4.83 | 4.83 |
| 485.54 | 4.75 | 4.75 |
| 380.40 | 3.55 | 3.55 |
| 439.43 | 3.93 | 3.93 |
| 471.51 | 4.44 | 4.44 |
| 493.54 | 3.89 | 3.89 |
| 475.48 | 4.27 | 4.27 |
| 442.47 | 4.63 | 4.63 |
| 471.51 | 4.44 | 4.44 |
| 428.44 | 4.37 | 4.37 |
| 437.47 | 4.17 | 4.17 |
| 457.49 | 4.13 | 4.13 |
| 506.58 | 4.91 | 4.91 |
| 459.41 | 3.97 | 3.97 |
| 435.46 | 3.83 | 3.83 |
| 443.46 | 3.52 | 3.52 |
| 352.35 | 2.77 | 2.77 |
| 493.54 | 3.68 | 3.68 |
| 534.47 | 4.51 | 4.51 |
| 525.48 | 5.15 | 5.15 |
| 429.43 | 3.65 | 3.65 |
| 458.52 | 3.91 | 3.91 |
| 458.47 | 4.46 | 4.46 |
| 454.46 | 2.34 | 2.34 |
| 449.51 | 4.04 | 4.04 |
| 496.44 | 5.39 | 5.39 |
| 457.49 | 4.13 | 4.13 |
| 458.43 | 3.76 | 3.76 |
| 525.48 | 5.15 | 5.15 |
| 472.45 | 3.85 | 3.85 |
| 447.49 | 3.84 | 3.84 |
| 471.51 | 4.44 | 4.44 |
| 498.41 | 4.96 | 4.96 |
| 470.53 | 5.36 | 5.36 |
| 459.50 | 3.99 | 3.99 |
| 419.39 | 3.36 | 3.36 |
| 471.51 | 4.44 | 4.44 |
| 433.46 | 3.75 | 3.75 |
| 456.50 | 5.02 | 5.02 |
| 447.49 | 3.79 | 3.79 |
| 458.52 | 3.91 | 3.91 |
| 536.38 | 4.89 | 4.89 |
| 419.48 | 4.03 | 4.03 |
| 414.42 | 4.06 | 4.06 |
| 432.41 | 4.20 | 4.20 |
| 471.51 | 4.44 | 4.44 |
| 471.51 | 4.44 | 4.44 |
| 471.51 | 4.44 | 4.44 |