Assay Report Card

Basic Information

ID: ALA4379616

Type: Functional

Description: Antiproliferative activity against human GIST48 cells harboring c-KIT exon 11 homozygous primary missense V560D mutant and exon 17 heterozygous secondary D820A mutant assessed as cell growth inhibition after 120 hrs by methylene blue staining based assay

Organism: Homo sapiens

Cell type: GIST48

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
398.483.333.33
493.624.594.59
482.825.695.69
417.973.193.19