Basic Information
ID: ALA4379617
Type: Functional
Description: Antiproliferative activity against human GIST430 cells harboring c-KIT exon 11 primary in-frame V560-L576 deletion mutant and exon 13 heterozygous secondary missense V654A mutant assessed as cell growth inhibition after 120 hrs by methylene blue staining based assay
Organism: Homo sapiens
Cell type: GIST430
Activity Charts
Bioactivity
Activity Types for Assay ALA4379617
GI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.48 | 3.33 | 3.33 |
| 493.62 | 4.59 | 4.59 |
| 482.82 | 5.69 | 5.69 |
| 417.97 | 3.19 | 3.19 |