Basic Information
ID: ALA4379665
Type: Functional
Description: In vivo inhibition of c-Kit in orally dosed NOD/SCID mouse xenografted with human GIST430 cells assessed as decrease in c-kit phosphorylation at Tyr703 residue measured after 16 hrs by immunoblot analysis
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4379665
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.97 | 3.19 | 3.19 |