Assay Report Card

Basic Information

ID: ALA4379672

Type: Functional

Description: Antitumor activity against human Kasumi-1 cells harboring c-kit exon 17 N822K mutant xenografted in SCID mouse assessed as tumor regression at 20 to 30 mg/kg, po qd administered at day 1 to 5 and 8 to 12 measured after 25 days by digital caliper method

Organism: Homo sapiens

Cell type: Kasumi 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
417.973.193.19