Assay Report Card

Basic Information

ID: ALA4379682

Type: Functional

Description: Antitumor activity against patient-derived human GS5107 cells harboring exon 13(K642E)/exon 17 (N822K) double mutant. xenografted in NOD/SCID mouse assessed as tumor growth inhibition at 15 mg/kg, po administered 5 days a week for 2 weeks measured after day 29 by digital caliper method relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
417.973.193.19