Basic Information
ID: ALA4379683
Type: Functional
Description: Antitumor activity against patient-derived human GS5107 cells harboring exon 13(K642E)/exon 17 (N822K) double mutant. xenografted in NOD/SCID mouse assessed as tumor growth inhibition at 30 mg/kg, po administered 5 days a week for 2 weeks measured after day 29 by digital caliper method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4379683
TGI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.82 | 5.69 | 5.69 |
| 417.97 | 3.19 | 3.19 |