Basic Information
ID: ALA4379687
Type: Binding
Description: Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ uptake by Fluo-4/AM dye based fluorescence microplate reader assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SH-SY5Y
Target: Voltage-gated L-type calcium channel(ALA2095229)
Document: ALA4376837
Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ uptake by Fluo-4/AM dye based fluorescence microplate reader assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4379687
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 232.28 | 1.86 | 1.86 |
| 194.19 | 1.50 | 1.50 |
| 346.34 | 2.18 | 2.18 |
| 486.61 | 3.92 | 3.92 |
| 505.06 | 4.96 | 4.96 |
| 470.61 | 4.30 | 4.30 |
| 456.58 | 3.91 | 3.91 |
| 535.48 | 4.67 | 4.67 |
| 486.61 | 3.92 | 3.92 |
| 456.58 | 3.91 | 3.91 |
| 470.61 | 4.30 | 4.30 |
| 484.64 | 4.69 | 4.69 |
| 500.64 | 4.31 | 4.31 |
| 514.66 | 4.70 | 4.70 |
| 484.64 | 4.69 | 4.69 |
| 549.51 | 5.06 | 5.06 |
| 491.03 | 4.57 | 4.57 |
| 500.64 | 4.31 | 4.31 |
| 498.66 | 5.08 | 5.08 |