Basic Information
ID: ALA4379716
Type: Binding
Description: Binding affinity to recombinant Cdc37 (unknown origin) assessed as inhibition of biotin labeled 3-[3-cyano-3-(4-fluorophenyl)prop-2-enoyl]oxypropyl(2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylate binding to enzyme at 0.25 to 0.5 uM incubated with compound for 2 hrs before or after incubation with biotin labeled 3-[3-cyano-3-(4-fluorophenyl)prop-2-enoyl]oxypropyl(2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylate for 2 hrs by pull down assay based immunoblot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4379716
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 681.85 | 8.84 | 8.84 |