Basic Information
ID: ALA4379767
Type: Functional
Description: Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimulated cAMP production after 30 mins in presence of CP55940 at EC20 concentration by hit-hunter cAMP assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: Cannabinoid CB1 receptor(ALA218)
Document: ALA4376840
Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimulated cAMP production after 30 mins in presence of CP55940 at EC20 concentration by hit-hunter cAMP assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4379767
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.38 | 5.52 | 5.52 |
| 360.39 | 5.38 | 5.38 |
| 360.39 | 5.38 | 5.38 |
| 342.40 | 5.24 | 5.24 |
| 360.39 | 5.38 | 5.38 |
| 343.39 | 4.64 | 4.64 |
| 396.37 | 5.66 | 5.66 |
| 396.37 | 5.66 | 5.66 |
| 378.38 | 5.52 | 5.52 |
| 378.38 | 5.52 | 5.52 |
| 360.39 | 5.38 | 5.38 |
| 360.39 | 5.38 | 5.38 |
| 378.38 | 5.52 | 5.52 |
| 396.37 | 5.66 | 5.66 |
| 360.39 | 5.38 | 5.38 |
| 396.37 | 5.66 | 5.66 |
| 343.39 | 4.64 | 4.64 |
| 343.39 | 4.64 | 4.64 |
| 343.39 | 4.64 | 4.64 |
| 343.39 | 4.64 | 4.64 |
| 343.39 | 4.64 | 4.64 |
| 360.39 | 5.38 | 5.38 |
| 360.39 | 5.38 | 5.38 |
| 360.39 | 5.38 | 5.38 |
| 361.38 | 4.78 | 4.78 |
| 343.39 | 4.64 | 4.64 |
| 343.39 | 4.64 | 4.64 |
| 343.39 | 4.64 | 4.64 |
| 360.39 | 5.38 | 5.38 |