ID: ALA4380042
Type: Binding
Description: Inverse agonist activity at human N-terminal His6-tagged RORgammat LBD (265 to 518 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition of N-terminal biotinylated co-activator SRC1 box2 peptide recruitment measured after 30 mins by TR-FRET assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4380042
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
444.80 | 5.76 | 5.76 |
367.71 | 5.38 | 5.38 |
431.30 | 5.77 | 5.77 |
504.82 | 6.77 | 6.77 |
522.89 | 6.18 | 6.18 |
478.88 | 7.05 | 7.05 |
486.83 | 6.63 | 6.63 |
486.83 | 6.63 | 6.63 |
500.86 | 6.31 | 6.31 |
486.83 | 6.63 | 6.63 |
488.85 | 6.70 | 6.70 |
542.94 | 7.89 | 7.89 |
462.81 | 6.58 | 6.58 |
522.91 | 8.14 | 8.14 |
424.76 | 5.27 | 5.27 |
461.83 | 6.32 | 6.32 |
472.85 | 6.99 | 6.99 |
500.86 | 6.56 | 6.56 |
472.85 | 6.99 | 6.99 |