Basic Information
ID: ALA4380047
Type: ADME
Description: Inverse agonist activity at His6-tagged PPARgamma LBD (unknown origin) assessed as inhibition of rosiglitazone-induced N-terminal biotinylated co-activator SRC1 box2 peptide recruitment measured after 30 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4380047
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.80 | 5.76 | 5.76 |
| 367.71 | 5.38 | 5.38 |
| 431.30 | 5.77 | 5.77 |
| 504.82 | 6.77 | 6.77 |
| 522.89 | 6.18 | 6.18 |
| 478.88 | 7.05 | 7.05 |
| 486.83 | 6.63 | 6.63 |
| 486.83 | 6.63 | 6.63 |
| 500.86 | 6.31 | 6.31 |
| 486.83 | 6.63 | 6.63 |
| 488.85 | 6.70 | 6.70 |
| 542.94 | 7.89 | 7.89 |
| 462.81 | 6.58 | 6.58 |
| 522.91 | 8.14 | 8.14 |
| 424.76 | 5.27 | 5.27 |
| 461.83 | 6.32 | 6.32 |
| 472.85 | 6.99 | 6.99 |
| 500.86 | 6.56 | 6.56 |
| 472.85 | 6.99 | 6.99 |