Basic Information
ID: ALA4380049
Type: Binding
Description: Inverse agonist activity at RORgammat in mouse EL4 cells assessed as inhibition of PMA/ionomycin-induced IL-17a production at 10 uM preincubated for 24 hrs followed by PMA/ionomycin stimulation and measured after 5 hrs by SYBR green dye based qRT-PCR analysis relative to control
Organism: Mus musculus
Cell type: EL4
Activity Charts
Bioactivity
Activity Types for Assay ALA4380049
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.80 | 5.76 | 5.76 |
| 462.81 | 6.58 | 6.58 |
| 461.83 | 6.32 | 6.32 |