Basic Information
ID: ALA4380061
Type: Binding
Description: Selectivity index, ratio of IC50 for human recombinant CYP1A2 to IC50 for human recombinant CYP1B1 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and NADPH-generating system by fluorometry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4380061
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.30 | 4.61 | 4.61 |
| 290.29 | 4.75 | 4.75 |
| 290.29 | 4.75 | 4.75 |
| 306.75 | 5.27 | 5.27 |
| 306.75 | 5.27 | 5.27 |
| 306.75 | 5.27 | 5.27 |
| 290.29 | 4.75 | 4.75 |
| 273.29 | 4.01 | 4.01 |
| 273.29 | 4.01 | 4.01 |
| 288.30 | 4.32 | 4.32 |
| 302.33 | 4.62 | 4.62 |
| 302.33 | 4.62 | 4.62 |
| 322.36 | 5.77 | 5.77 |
| 308.28 | 4.89 | 4.89 |
| 340.30 | 5.63 | 5.63 |
| 287.32 | 4.54 | 4.54 |
| 322.82 | 5.74 | 5.74 |
| 322.82 | 5.74 | 5.74 |
| 362.38 | 4.64 | 4.64 |
| 321.76 | 5.20 | 5.20 |
| 288.37 | 5.98 | 5.98 |
| 320.37 | 3.85 | 3.85 |
| 306.36 | 6.12 | 6.12 |
| 273.29 | 4.01 | 4.01 |
| 321.76 | 5.20 | 5.20 |
| 370.45 | 4.37 | 4.37 |
| 322.82 | 5.74 | 5.74 |
| 354.81 | 4.50 | 4.50 |
| 322.82 | 6.64 | 6.64 |
| 378.45 | 6.01 | 6.01 |
| 404.90 | 5.02 | 5.02 |
| 357.41 | 4.45 | 4.45 |
| 336.77 | 5.28 | 5.28 |
| 341.19 | 5.92 | 5.92 |
| 306.36 | 5.22 | 5.22 |
| 318.40 | 5.99 | 5.99 |
| 322.82 | 6.64 | 6.64 |
| 306.36 | 6.12 | 6.12 |
| 315.37 | 4.68 | 4.68 |
| 306.36 | 6.12 | 6.12 |
| 288.37 | 5.08 | 5.08 |
| 370.45 | 4.37 | 4.37 |