Basic Information
ID: ALA4380062
Type: Binding
Description: Potency index, ratio of IC50 for ANF to IC50 for test compound for inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and NADPH-generating system incubated for 35 mins by fluorometry
Format: BAO_0000357
Organism: Homo sapiens
Target: Cytochrome P450 1B1(ALA4878)
Document: ALA4376853
Potency index, ratio of IC50 for ANF to IC50 for test compound for inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and NADPH-generating system incubated for 35 mins by fluorometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4380062
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 306.75 | 5.27 | 5.27 |
| 340.30 | 5.63 | 5.63 |
| 322.82 | 6.64 | 6.64 |
| 404.90 | 5.02 | 5.02 |
| 357.41 | 4.45 | 4.45 |