ID: ALA4380147
Type: ADME
Description: Prodrug conversion in porcine liver mitochondrial membrane vesicles assessed as N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine formation at 3 mM and pH 6 preincubated for 3 mins followed by NADH addition measured after 20 mins under aerobic conditions by RP-HPLC analysis
Organism: Sus scrofa
Tissue: Liver
Subcellular Fraction: Mitochondrial membrane vesicle
Bioactivity
Activity Types for Assay ALA4380147
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
204.27 | -0.70 | -0.70 |