Assay Report Card

Basic Information

ID: ALA4380152

Type: ADME

Description: Prodrug conversion in porcine liver mitochondria assessed as N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine formation at 3 mM and pH 6 preincubated for 3 mins followed by NADH addition measured after 20 mins under aerobic conditions by RP-HPLC analysis

Organism: Sus scrofa

Tissue: Liver

Subcellular Fraction: Mitochondria

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
204.27-0.70-0.70