Basic Information
ID: ALA4380159
Type: ADME
Description: Inhibition of recombinant human C-terminal His6-tagged ERAP2 expressed in baculovirus infected BTA-TN-5B1-4 insect cells using R-AMC as substrate measured after 1 hr by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4380159
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.40 | 2.49 | 2.49 |
| 458.46 | 4.20 | 4.20 |
| 419.57 | 3.98 | 3.98 |
| 343.43 | 1.15 | 1.15 |
| 345.45 | 1.40 | 1.40 |
| 428.43 | 4.19 | 4.19 |
| 401.51 | 2.03 | 2.03 |
| 389.48 | 2.16 | 2.16 |
| 473.47 | 2.96 | 2.96 |
| 385.51 | 2.32 | 2.32 |
| 462.88 | 4.85 | 4.85 |
| 344.46 | 2.49 | 2.49 |
| 472.49 | 4.23 | 4.23 |
| 371.49 | 2.02 | 2.02 |
| 404.49 | 3.49 | 3.49 |
| 390.46 | 3.18 | 3.18 |
| 507.33 | 4.96 | 4.96 |
| 405.93 | 2.67 | 2.67 |
| 408.45 | 3.32 | 3.32 |