Assay Report Card

Basic Information

ID: ALA4380408

Type: Binding

Description: Binding affinity to Plasmodium falciparum NMT (27 to 410 residues) expressed in Escherichia coli Rosetta (DE3) assessed as change in melting temperature at 100 uM in absence of 100 uM myristoyl-CoA by Sypro orange dye based differential scanning fluorimetry (Rvb = 0 degreeC)

Organism: Plasmodium falciparum

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
444.564.644.64
348.453.113.11
498.004.934.93
362.264.574.57
423.903.783.78