Basic Information
ID: ALA4380427
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes at 20 uM using dextromethorphan as substrate incubated for 60 mins by HPLC analysis relative to control
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4380427
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.39 | 5.36 | 5.36 |
| 524.50 | 5.23 | 5.23 |
| 458.44 | 4.57 | 4.57 |
| 500.50 | 5.26 | 5.26 |
| 456.42 | 3.91 | 3.91 |