Basic Information
ID: ALA4380429
Type: Functional
Description: Antagonist activity at human EP4 expressed in CHO cells coexpressing G16-alpha assessed as intracellular calcium flux preincubated for 15 mins followed by addition of PGE2 by calcium flux assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4380429
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.39 | 5.36 | 5.36 |
| 474.49 | 4.35 | 4.35 |
| 484.43 | 4.79 | 4.79 |
| 458.44 | 4.57 | 4.57 |
| 474.49 | 4.33 | 4.33 |
| 426.48 | 4.18 | 4.18 |
| 444.47 | 4.32 | 4.32 |
| 462.46 | 4.46 | 4.46 |
| 486.37 | 4.55 | 4.55 |
| 486.37 | 4.55 | 4.55 |
| 484.48 | 5.10 | 5.10 |
| 456.50 | 4.19 | 4.19 |
| 444.41 | 4.01 | 4.01 |
| 450.39 | 3.87 | 3.87 |
| 524.50 | 5.23 | 5.23 |
| 486.37 | 4.55 | 4.55 |
| 456.50 | 4.19 | 4.19 |
| 436.37 | 3.67 | 3.67 |
| 494.47 | 5.20 | 5.20 |
| 494.47 | 5.20 | 5.20 |
| 486.49 | 5.19 | 5.19 |
| 466.39 | 3.70 | 3.70 |
| 434.50 | 3.56 | 3.56 |
| 460.46 | 4.49 | 4.49 |
| 432.40 | 3.84 | 3.84 |
| 458.44 | 4.41 | 4.41 |
| 432.40 | 3.84 | 3.84 |
| 458.44 | 4.57 | 4.57 |
| 418.38 | 3.53 | 3.53 |
| 436.37 | 3.67 | 3.67 |
| 486.53 | 4.20 | 4.20 |
| 500.52 | 5.58 | 5.58 |
| 514.53 | 5.57 | 5.57 |
| 450.46 | 4.00 | 4.00 |
| 500.48 | 4.34 | 4.34 |
| 460.46 | 4.49 | 4.49 |
| 458.44 | 4.26 | 4.26 |
| 500.50 | 5.26 | 5.26 |
| 418.38 | 3.53 | 3.53 |
| 512.46 | 5.34 | 5.34 |
| 494.47 | 5.20 | 5.20 |
| 498.51 | 5.49 | 5.49 |
| 524.50 | 5.23 | 5.23 |
| 470.45 | 4.50 | 4.50 |
| 450.39 | 3.87 | 3.87 |
| 432.52 | 4.71 | 4.71 |
| 466.39 | 3.70 | 3.70 |
| 446.43 | 4.10 | 4.10 |
| 486.37 | 4.55 | 4.55 |
| 446.43 | 4.10 | 4.10 |
| 472.47 | 4.80 | 4.80 |
| 456.42 | 3.91 | 3.91 |