Basic Information
ID: ALA4380479
Type: Binding
Description: Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer-Thr-FAM peptide as substrate after 1 hr by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4380479
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 488.56 | 4.42 | 4.42 |
| 458.54 | 4.41 | 4.41 |
| 476.53 | 4.55 | 4.55 |
| 498.39 | 5.10 | 5.10 |
| 540.64 | 5.48 | 5.48 |
| 501.56 | 4.94 | 4.94 |
| 515.59 | 4.08 | 4.08 |
| 486.57 | 5.11 | 5.11 |
| 476.98 | 5.36 | 5.36 |
| 503.02 | 5.63 | 5.63 |
| 512.51 | 5.30 | 5.30 |
| 519.64 | 5.50 | 5.50 |
| 501.60 | 5.49 | 5.49 |
| 456.57 | 5.02 | 5.02 |
| 501.60 | 5.59 | 5.59 |
| 497.40 | 5.71 | 5.71 |
| 428.51 | 4.40 | 4.40 |
| 442.54 | 4.71 | 4.71 |
| 462.96 | 5.05 | 5.05 |
| 460.53 | 4.85 | 4.85 |
| 514.60 | 4.68 | 4.68 |
| 497.40 | 5.71 | 5.71 |