Basic Information
ID: ALA4380521
Type: Functional
Description: Antiproliferative activity against human SK-MEL-2 cells harboring NRAS/TP53 mutation assessed as reduction in cell viability after 96 hrs by CellTiter-Glo luminescence assay
Organism: Homo sapiens
Cell type: SK-MEL-2
Activity Charts
Bioactivity
Activity Types for Assay ALA4380521
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 591.48 | 4.75 | 4.75 |
| 552.61 | 5.13 | 5.13 |
| 566.63 | 5.52 | 5.52 |
| 498.51 | 3.70 | 3.70 |
| 472.48 | 3.74 | 3.74 |
| 458.53 | 3.11 | 3.11 |
| 538.58 | 4.43 | 4.43 |
| 539.57 | 3.82 | 3.82 |
| 512.54 | 4.18 | 4.18 |
| 580.62 | 5.10 | 5.10 |
| 514.51 | 4.22 | 4.22 |
| 515.54 | 3.44 | 3.44 |
| 443.43 | 3.17 | 3.17 |
| 432.53 | 3.59 | 3.59 |
| 484.52 | 3.61 | 3.61 |
| 526.52 | 4.23 | 4.23 |
| 538.58 | 4.57 | 4.57 |
| 472.55 | 3.50 | 3.50 |
| 509.54 | 4.67 | 4.67 |
| 434.50 | 2.17 | 2.17 |
| 514.47 | 3.30 | 3.30 |
| 553.59 | 4.38 | 4.38 |
| 574.01 | 4.47 | 4.47 |
| 524.55 | 4.62 | 4.62 |
| 568.60 | 5.10 | 5.10 |
| 490.57 | 4.11 | 4.11 |
| 542.57 | 4.55 | 4.55 |
| 500.49 | 3.66 | 3.66 |
| 510.52 | 4.06 | 4.06 |
| 514.51 | 4.22 | 4.22 |
| 486.50 | 4.13 | 4.13 |
| 554.58 | 4.46 | 4.46 |
| 472.55 | 3.50 | 3.50 |
| 390.45 | 2.47 | 2.47 |
| 514.51 | 4.22 | 4.22 |
| 454.49 | 3.44 | 3.44 |
| 525.54 | 3.80 | 3.80 |