Basic Information
ID: ALA4380523
Type: Binding
Description: Inhibition of recombinant full length human His-tagged CDK9/CyclinT1 expressed in baculovirus expression system using biotin-labelled Ttds-YISPLKSPYKISEG peptide as substrate preincubated with enzyme for 15 mins followed by substrate addition and further incubated for 25 mins presence of 10 uM of ATP by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4380523
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 552.61 | 5.13 | 5.13 |
| 566.63 | 5.52 | 5.52 |
| 498.51 | 3.70 | 3.70 |
| 538.58 | 4.43 | 4.43 |
| 539.57 | 3.82 | 3.82 |
| 512.54 | 4.18 | 4.18 |
| 580.62 | 5.10 | 5.10 |
| 515.54 | 3.44 | 3.44 |
| 443.43 | 3.17 | 3.17 |
| 526.52 | 4.23 | 4.23 |
| 538.58 | 4.57 | 4.57 |
| 509.54 | 4.67 | 4.67 |
| 553.59 | 4.38 | 4.38 |
| 574.01 | 4.47 | 4.47 |
| 524.55 | 4.62 | 4.62 |
| 568.60 | 5.10 | 5.10 |
| 542.57 | 4.55 | 4.55 |
| 500.49 | 3.66 | 3.66 |
| 510.52 | 4.06 | 4.06 |
| 514.51 | 4.22 | 4.22 |
| 554.58 | 4.46 | 4.46 |
| 525.54 | 3.80 | 3.80 |