Basic Information
ID: ALA4380524
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed in sf21 cells using biotin labelled Ahx-GGEEEEYFELVKKKK peptide as substrate preincubated with enzyme for 15 mins followed by substrate addition and further incubated for 45 mins in presence of 10 uM of ATP by TR-FRET assay
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA4380524
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 552.61 | 5.13 | 5.13 |
| 566.63 | 5.52 | 5.52 |
| 498.51 | 3.70 | 3.70 |
| 538.58 | 4.43 | 4.43 |
| 539.57 | 3.82 | 3.82 |
| 512.54 | 4.18 | 4.18 |
| 580.62 | 5.10 | 5.10 |
| 526.52 | 4.23 | 4.23 |
| 538.58 | 4.57 | 4.57 |
| 509.54 | 4.67 | 4.67 |
| 553.59 | 4.38 | 4.38 |
| 574.01 | 4.47 | 4.47 |
| 524.55 | 4.62 | 4.62 |
| 568.60 | 5.10 | 5.10 |
| 542.57 | 4.55 | 4.55 |
| 500.49 | 3.66 | 3.66 |
| 510.52 | 4.06 | 4.06 |
| 514.51 | 4.22 | 4.22 |
| 554.58 | 4.46 | 4.46 |
| 525.54 | 3.80 | 3.80 |