Basic Information
ID: ALA4380724
Type: Binding
Description: Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at up to 1 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCC827
Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)
Document: ALA4376874
Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at up to 1 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4380724
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 860.34 | 3.60 | 3.60 |
| 872.40 | 5.14 | 5.14 |
| 1036.56 | ||
| 901.44 | 5.89 | 5.89 |