Basic Information
ID: ALA4380732
Type: Binding
Description: Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at >=50 nM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCC827
Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)
Document: ALA4376874
Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at >=50 nM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4380732
%max
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 901.44 | 5.89 | 5.89 |