Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at 100 nM treated 8 hrs post seru...

Basic Information

ID: ALA4380771

Type: Binding

Description: Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at 100 nM treated 8 hrs post serum starvation measured after 12 hrs by Western blot analysis relative to control

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HCC827

Target:  Protein cereblon/Epidermal growth factor receptor(ALA4523680)

Document:  ALA4376874

Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at 100 nM treated 8 hrs post serum starvation measured after 12 hrs by Western blot analysis relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
901.445.895.89