Basic Information
ID: ALA4380781
Type: Binding
Description: Protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation at 100 nM measured after 8 hrs in presence of neddylation inhibitor MLN4924 by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)
Document: ALA4376874
Protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation at 100 nM measured after 8 hrs in presence of neddylation inhibitor MLN4924 by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4380781
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 901.44 | 5.89 | 5.89 |