Basic Information
ID: ALA4380785
Type: Binding
Description: Protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation at 100 nM measured after 8 hrs in presence of CRBN E3 ligase binder thalidomide by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4380785
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 901.44 | 5.89 | 5.89 |