Basic Information
ID: ALA4380789
Type: Binding
Description: Reversible protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as recovery of EGFR degradation at 100 nM preincubated for 12 hrs followed by compound washout and measured after 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HCC827
Activity Charts
Bioactivity
Activity Types for Assay ALA4380789
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 901.44 | 5.89 | 5.89 |