Basic Information
ID: ALA4380795
Type: Binding
Description: Reversible protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as recovery of EGFR degradation at 100 nM preincubated for 12 hrs followed by compound washout and measured up to 48 hrs by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4380795
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 901.44 | 5.89 | 5.89 |