Basic Information
ID: ALA4380816
Type: Binding
Description: Inhibition of recombinant human C-terminal GST-tagged BCL6 BTB domain C8Q/C67R/C84N triple mutant expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in SMRT/BTB domain interaction incubated for 1 hr by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4380816
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.84 | 3.53 | 3.53 |
| 312.73 | 2.43 | 2.43 |
| 365.84 | 3.21 | 3.21 |
| 451.51 | 3.20 | 3.20 |
| 530.40 | 3.96 | 3.96 |
| 351.81 | 2.77 | 2.77 |
| 522.61 | 5.13 | 5.13 |
| 567.09 | 6.19 | 6.19 |
| 519.38 | 4.16 | 4.16 |
| 340.79 | 3.21 | 3.21 |
| 532.65 | 5.54 | 5.54 |
| 469.50 | 3.34 | 3.34 |
| 296.73 | 3.45 | 3.45 |
| 529.41 | 4.57 | 4.57 |
| 562.67 | 5.54 | 5.54 |
| 350.83 | 4.77 | 4.77 |
| 536.68 | 5.83 | 5.83 |
| 310.76 | 3.84 | 3.84 |
| 337.79 | 2.43 | 2.43 |
| 326.76 | 2.82 | 2.82 |
| 522.65 | 5.44 | 5.44 |
| 529.41 | 4.57 | 4.57 |
| 546.67 | 5.84 | 5.84 |
| 324.79 | 4.23 | 4.23 |
| 535.44 | 4.63 | 4.63 |
| 530.40 | 3.96 | 3.96 |
| 519.38 | 4.16 | 4.16 |
| 380.90 | 5.14 | 5.14 |
| 506.61 | 5.02 | 5.02 |
| 535.44 | 4.63 | 4.63 |
| 364.85 | 4.50 | 4.50 |
| 338.77 | 2.86 | 2.86 |