Basic Information
ID: ALA4380946
Type: Binding
Description: Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKNRFVV-NH2 peptide as substrate preincubated with enzyme for 10 mins followed by substrate addition after 60 mins in presence of ATP by caliper mobility shift assay
Format: BAO_0000219
Organism: Homo sapiens
Target: MAP kinase-interacting serine/threonine-protein kinase MNK1(ALA4718)
Document: ALA4376877
Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKNRFVV-NH2 peptide as substrate preincubated with enzyme for 10 mins followed by substrate addition after 60 mins in presence of ATP by caliper mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4380946
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 160.18 | 1.58 | 1.58 |
| 239.30 | 3.27 | 3.27 |
| 192.24 | 2.10 | 2.10 |
| 170.22 | 2.33 | 2.33 |
| 193.64 | 2.31 | 2.31 |
| 170.62 | 2.34 | 2.34 |
| 295.31 | 2.97 | 2.97 |
| 350.42 | 3.34 | 3.34 |
| 325.41 | 3.23 | 3.23 |
| 350.42 | 3.64 | 3.64 |
| 392.46 | 3.46 | 3.46 |
| 267.33 | 1.79 | 1.79 |
| 213.24 | 1.43 | 1.43 |
| 205.24 | 2.51 | 2.51 |
| 256.30 | 2.63 | 2.63 |
| 228.08 | 2.76 | 2.76 |
| 213.24 | 1.43 | 1.43 |
| 274.32 | 3.51 | 3.51 |
| 296.37 | 3.56 | 3.56 |
| 232.67 | 2.50 | 2.50 |
| 228.25 | 1.86 | 1.86 |
| 336.40 | 3.04 | 3.04 |
| 278.31 | 2.25 | 2.25 |
| 362.43 | 3.90 | 3.90 |
| 228.25 | 1.86 | 1.86 |
| 341.41 | 2.47 | 2.47 |
| 268.32 | 2.78 | 2.78 |
| 242.23 | 1.55 | 1.55 |
| 241.29 | 2.28 | 2.28 |
| 212.25 | 2.16 | 2.16 |
| 297.36 | 1.98 | 1.98 |
| 212.25 | 2.11 | 2.11 |
| 198.22 | 1.85 | 1.85 |
| 185.23 | 2.24 | 2.24 |
| 214.22 | 1.55 | 1.55 |
| 232.67 | 2.50 | 2.50 |
| 228.25 | 1.86 | 1.86 |
| 257.29 | 1.18 | 1.18 |
| 199.21 | 2.45 | 2.45 |
| 240.26 | 2.05 | 2.05 |
| 278.31 | 2.25 | 2.25 |
| 228.25 | 1.86 | 1.86 |
| 336.40 | 3.33 | 3.33 |
| 245.23 | 2.81 | 2.81 |
| 213.24 | 1.43 | 1.43 |
| 275.31 | 2.91 | 2.91 |
| 283.33 | 1.59 | 1.59 |
| 313.36 | 1.99 | 1.99 |
| 324.34 | 1.81 | 1.81 |
| 378.43 | 3.07 | 3.07 |
| 364.45 | 4.08 | 4.08 |
| 242.28 | 2.25 | 2.25 |
| 212.25 | 2.16 | 2.16 |